BioRePeel Cl3™ — biphasic medical peel and biostimulation
A patented, biphasic medical peel with a strongly revitalising, moisturising and biostimulating effect. It exfoliates while at the same time stimulating the skin to produce growth factors — without heavy peeling and without taking you away from your daily activities.
What is BioRePeel Cl3
BioRePeel Cl3™ is a patented, biphasic medical peel (a medical device) with a strongly rejuvenating, revitalising and moisturising effect. It works on both the outer and inner layers of the skin — through its exfoliating and keratolytic action it removes dead epidermal cells, while at the level of the dermis it activates cells to intensively produce growth factors (PDGF, alpha and beta 1 TGF, and VEGF), leading to strong biostimulation of the skin.
The preparation consists of two phases: a hydrophilic one (including trichloroacetic acid 35%, lactobionic, salicylic, tartaric and citric acid, vitamins C and B2, amino acids and gamma-aminobutyric acid) and a lipophilic one (squalene and isopropyl myristate), which protects the hydrophilic layer from oxidation and stabilises the formula. This is why BioRePeel works deeply while not causing heavy, uncomfortable peeling.
See the details
BioRePeel vs other peels — what sets it apart
BioRePeel Cl3 is a biphasic biostimulating peel — it combines exfoliation with stimulating the skin to produce growth factors, with virtually no heavy peeling. It is one of our medical chemical peels; we also work with Mesopeel Mesoestetic, Mediderma by Sesderma and the lifting PQ Age.
To enhance the effect, BioRePeel can be combined with Dermapen 4 microneedle mesotherapy — a popular combined protocol. For persistent pigmentation and melasma, we choose Cosmelan or laser. The choice is made by a cosmetologist.
Source: Versum and Booksy reports, as of 30.06.2026 (approximate matching). No revenue data included.
What the biphasic action of BioRePeel Cl3 involves
Hydrophilic phase
TCA acid 35% with a complex of acids, vitamins and amino acids — exfoliates, revitalises and brightens the skin.
Lipophilic phase
Squalene and isopropyl myristate protect the formula from oxidation and stabilise the preparation — action without heavy peeling.
Biostimulation
At the level of the dermis it activates the production of growth factors (PDGF, TGF, VEGF) — strong stimulation of regeneration.
BioRePeel is minimally invasive and comfortable for most patients — with sensitive skin, a slight burning sensation may be felt. It can be used on the face, neck, décolletage, hands, elbows, knees and feet, all year round and with no age restrictions.
Indications for the BioRePeel Cl3 treatment
What we treat with BioRePeel Cl3
We use this treatment for 2 indications. It works a little differently in each of them — below we describe exactly what it does in each case.
Skin pigmentation
The biphasic formula exfoliates and biostimulates at the same time, with no visible skin peeling. For pigmentation and uneven skin tone, it is an option for those who cannot afford several days of downtime.
02Active acne
BioRePeel works for both comedonal and active acne — it regulates sebum production and calms inflammation. It is often the first step before introducing laser treatment.
Unsure which indication describes your situation? See all the indications or ask during a consultation.
Want to refresh and biostimulate your skin without heavy peeling? Book a BioRePeel consultation.
Book a consultationWhat research says about TCA peels and biostimulation
The publications below concern peels with trichloroacetic acid (TCA) — the main ingredient of BioRePeel — and the role of growth factors in skin remodelling.
TCA peel and collagen remodelling
A histometric, immunohistochemical and ultrastructural study showed a beneficial effect of TCA peels on collagen renewal in photoaged skin.
El-Domyati et al., Dermatol Surg 2004 · PubMed →TCA peel — an RCT study
A randomised, controlled clinical trial assessed a novel TCA peel as an anti-ageing therapy for facial skin in postmenopausal women.
Piejko et al., Postepy Dermatol Alergol 2025 · PubMed →The role of TGF-β in skin remodelling
A scientific review described the TGF-β/Smad signalling pathway as key to the processes of healing and remodelling of skin tissue.
Zhang et al., Biomed Pharmacother 2020 · PubMed →The cited studies concern TCA peels and the growth-factor mechanism (at the level of the ingredient/mechanism), not a specific preparation. The number of treatments is determined by a cosmetologist; results vary from person to person.
Step by step — the BioRePeel treatment
The treatment begins with a consultation and a health history interview. BioRePeel requires no prior preparation from the client and can be performed at any time of year. The treatment itself is short and pleasant — after the skin is cleansed, the preparation is massaged in and removed after the appropriate time. It is minimally invasive and comfortable for most patients; with sensitive skin, a slight burning sensation may be felt. The peel does not take you away from your daily activities and does not cause heavy peeling.
Consultation and health history
Ruling out contraindications and assessing the skin.
Cleansing the skin
Preparing the treatment area.
Massaging in the preparation
Applying the biphasic peel and timing it precisely.
Removal and protection
Rinsing off the preparation, moisturiser and sun protection.
Recommendations after a BioRePeel treatment
BioRePeel does not cause heavy peeling and does not take you away from your daily activities. To maintain the effect, a series of 4–8 treatments every 2–3 weeks is recommended.
Sun protection
Use SPF — it supports the brightening effect and protects freshly renewed skin.
Gentle skincare
For a few days, avoid irritating substances and strong acids in your home-care regimen.
Avoid irritation
Postpone treatments that irritate the skin (laser, hair removal) as advised by your cosmetologist.
Combine with Dermapen
To enhance the effect, BioRePeel can be combined with Dermapen microneedle mesotherapy.
Stick to the series
The optimal effect comes from a series of 4–8 treatments every 2–3 weeks.
Educational information. Detailed guidance is provided by your specialist; results and the course of treatment vary from person to person.
See the treatment room and the procedure — BioRePeel
Authentic photographs from our Velvet Skin Clinic locations in Warsaw (Świętokrzyska — City Centre, Niepodległości — Mokotów).
BioRePeel Cl3 — treatment price in Warsaw
The price depends on the area and the number of treatments. BioRePeel is based on a series — usually 4–8 treatments every 2–3 weeks. It can be combined with Dermapen microneedle mesotherapy. We agree the plan during a consultation.
Key parameters
See also — peels and related therapies
„Wonderful staff. She answered all my questions. And the treatment itself was carried out very professionally, in a lovely atmosphere." (translated from Polish)
Aleksandra · 2022review from Booksy„The treatment with BHA acids was my first experience with this kind of skincare and I’m pleased with it. My skin looks healthier, is less oily, and blemishes heal faster. A perfect balance between results and gentleness." (translated from Polish)
Gertruda Oczkowska · 2026review from Google„A nice selection of chemical peels, modern methods. I recommend it." (translated from Polish)
Halina Porada · 2024review from GoogleContraindications for the BioRePeel peel
Every case is assessed individually by a cosmetologist during the consultation interview. The main contraindications:
Frequently asked questions — BioRePeel Cl3
What is BioRePeel Cl3 and how does it work?
BioRePeel Cl3 is a patented, biphasic medical peel with TCA acid 35%. It exfoliates and renews the epidermis through keratolytic action, while at the level of the dermis it stimulates the production of growth factors (PDGF, TGF, VEGF), strongly biostimulating the skin. The lipophilic phase means it works deeply, but without heavy peeling.
Does BioRePeel cause skin peeling?
No — this is one of the main advantages of the treatment. BioRePeel is minimally invasive and comfortable for most patients, it does not cause heavy, uncomfortable peeling and does not take you away from your daily activities. With sensitive skin, only a slight burning sensation may be felt.
What skin concerns does BioRePeel help with?
BioRePeel works well for pigmentation and uneven skin tone, active and comedonal acne, loss of firmness and elasticity, and fine lines. It has a revitalising and biostimulating effect, and can also be used on the neck, décolletage, hands and other areas of the body.
Can BioRePeel be combined with Dermapen?
Yes. BioRePeel is a stand-alone treatment, but to enhance the therapeutic effects it is often combined with Dermapen microneedle mesotherapy. This is a popular combined protocol — a cosmetologist decides whether it is appropriate after assessing the skin.
How many BioRePeel treatments are needed?
Even the first treatment gives a visible effect, but to maintain the result a series of 4–8 treatments every 2–3 weeks is recommended. The number of treatments depends on the skin type and indication, and is determined by a cosmetologist during the consultation.
How much does BioRePeel Cl3 cost in Warsaw?
The price of a BioRePeel treatment starts from 300 zł and depends on the area and the number of treatments in the series. An exact quote (including for the protocol combined with Dermapen) is agreed during the consultation; you will find the full price list on our pricing page.
Treatments are performed by our cosmetologists
Treatments at Velvet Skin Clinic are performed by certified cosmetologists with many years of experience in laser therapy, hi-tech devices and skin care treatments. After a consultation, we match the method and the specialist to your skin and your goal.
Book your treatment — Velvet Skin Clinic
ul. Świętokrzyska 30
00-116 Warsaw · opposite the Palace of Culture and Science
tel. 500 53 30 30
See what the research says
The publications we base this treatment page on — with PMID identifiers and an assessment of the strength of evidence.